
3D TEE in Interatrial Septum Imaging: Insights from a Rare Anatomical Anomaly
- Posted by Mohamed Abdelwahab
- Date March 28, 2026
- Comments 0 comment
Imaging the interatrial septum (IAS) is a fundamental part of transesophageal echocardiography (TEE), especially in:
- Transseptal puncture
- Structural heart interventions
- Congenital and acquired septal abnormalities
While 2D TEE provides useful information, it is often limited in fully characterizing complex septal anatomy.
With the advancement of real-time 3D transesophageal echocardiography (3D TEE), we now have the ability to visualize the IAS in its true anatomical form.
📄 Original Image Case Publication
Read the original case here:
👉 https://pubmed.ncbi.nlm.nih.gov/25411253/
🎥 Watch: How to Image the Interatrial Septum (RATLe-90 Maneuver)
To master IAS imaging using 3D TEE, watch this open-access CIC lecture:
🎯 This lecture covers:
- Standard IAS imaging views
- 3D TEE acquisition
- RATLe-90 maneuver
- Practical tips for clinical use
Case Overview: A Rare Interatrial Septal Anomaly
A 51-year-old female with severe mitral regurgitation underwent TEE evaluation.
🔍 Findings:
- On 2D TEE:
- A ridge-like structure was seen on the left atrial side of the IAS
- On 3D TEE:
- The structure was clearly visualized as:
- A longitudinal ridge from the left atrial perspective
- A corresponding depression on the right atrial side
- The structure was clearly visualized as:
📌 As demonstrated in the images of the article, 3D TEE provided a complete spatial understanding of this structure that was not fully appreciated in 2D
Understanding the Anatomy
This rare anomaly is thought to result from:
👉 Abnormal fusion between:
- Septum primum
- Septum secundum
This leads to:
- Prominent enfolding toward the left atrium
- Corresponding depression on the right atrium
Why 3D TEE Was Critical
❌ Limitations of 2D TEE:
- Shows only slices
- Cannot fully represent spatial relationships
- May miss complex morphology
✅ Advantages of 3D TEE:
- En face visualization of IAS
- True anatomical orientation
- Simultaneous visualization of both atrial aspects
This is clearly illustrated in the multi-panel images of the publication, where 3D imaging reveals the full geometry of the septum
Clinical Implications
Understanding such anatomical variations is crucial for:
🔹 1. Transseptal Procedures
- Avoid incorrect puncture sites
- Prevent complications
🔹 2. Structural Heart Interventions
- MitraClip
- LAA closure
- ASD/PFO procedures
🔹 3. Accurate Diagnosis
- Avoid misinterpretation of unusual structures
The Role of Standardized 3D Imaging (RATLe-90)
To consistently visualize the IAS:
👉 The RATLe-90 maneuver provides:
- Anatomically oriented en face view
- Better spatial understanding
- Standardized imaging approach
🎥 (Explained step-by-step in the lecture above)
From Rare Cases to Daily Practice
Although this is a rare anomaly, the key message is broader:
💡 3D TEE should be routinely used for IAS assessment
Because:
- Many subtle anatomical variations exist
- These variations can affect procedural outcomes
- 3D imaging reduces uncertainty
🎓 Learn Advanced 3D TEE & Structural Echo
If you want to master:
- Interatrial septum imaging
- 3D TEE acquisition
- Transseptal guidance
- Structural heart procedures
👉 Explore CIC Online Echocardiography Courses:
🔗 https://ciceg.net/cic-courses/
✔️ Real clinical cases
✔️ Practical step-by-step teaching
✔️ On-demand access
✔️ Designed for cardiologists worldwide
Conclusion
This case highlights the incremental value of 3D TEE in understanding complex interatrial septal anatomy.
By providing true anatomical visualization, 3D TEE:
- Enhances diagnostic accuracy
- Improves procedural planning
- Reduces complications
It reinforces a key concept:
👉 “If you want to understand anatomy… think in 3D, not 2D.”


